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Figure Caption
Fig. 6
Increasing lysosomal biogenesis moderately protects against myofiber detachment in caf zebrafish. (A) Lysosomal biogenesis transcription factor TFEB increases the number of lysosomes in myofibers, however not significantly (P = 0.1200). (B) Confocal micrographs illustrating GFP-expressing myofibers in WT embryos. (C) Confocal micrographs illustrating GFP-expressing myofibers in caf mutant embryos (detached fibers: TFEB-GFP = 33.9%; PLCĪ“-PH-GFP = 45.4%; P = 0.0065).
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