ZFIN Image: Li et al., 2022, Fig. 1

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Figure Caption

Fig. 1

Determination of CoCl₂ concentration for the cell hypoxia model. (A) Cell proliferation was tested by CCK-8 assay. The 0nM CoCl2 treated group was chosen as control. (B) The mRNA expression of VEGFA and HIF1A in HRVECs was tested after 24 hours of CoCl₂ exposure. Values are expressed as the mean ± SD. VEGFA, vascular endothelial growth factor A; HIF1A, hypoxia-inducible factor 1-alpha. Normoxia group was set as the control at 100%. * Significant difference among CoCl₂ with various concentrations (100 µM, 150 µM, and 200 µM; paired t-test, P < 0.05). ^# Significant difference of CoCl₂ groups (100 µM, 150 µM, and 200 µM) compared with the control normoxia group (paired t-test, P values < 0.05).

Acknowledgments

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