ZFIN Image: Shi et al., 2023, Figure 3

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Figure Caption

Figure 3

Cell subtypes in the zebrafish inner ear end organs.

(A–D) Integration and analysis of single-cell RNAseq data generated by sci-Seq (sci) or 10x Chromium sequencing (10x) for inner ear hair cells and supporting cells from embryonic (sci), larval (sci,10x), and adult (10x) stages. UMAP projection of cells are grouped by (A) dataset of origin and (B) timepoint. (C) Unsupervised clustering divides cells into 10 clusters that were grouped into 9 cell subtypes. (D) Feature plots showing hair cell marker myo6b, nascent hair cell marker dla, supporting cell marker lfng, and putative progenitor marker fgfr2 expression in the integrated dataset. (E) Differentially expressed genes across the 10 cell clusters.

Acknowledgments

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