ZFIN Image: Brandt et al., 2021, Fig. 4

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Fig. 4

Macrophage ablation exacerbated hyperopia in mfrp^?/? zebrafish. (A) Representative SD-OCT B-scans from the center of mfrp^+/^?; mpeg1:NTR-eYFP⁺ eyes and their mfrp^?^/^?; mpeg1:NTR-eYFP⁺ siblings with or without MTZ treatment. (B) Eye size metrics of mfrp⁺^/^?; mpeg1:NTR-eYFP⁺ and mfrp^?^/^?; mpeg1:NTR-eYFP⁺ fish with or without MTZ treatment. (C) Axial length normalized to body length and lens diameter. (D) Relative refractive error. Two-way ANOVA was used for statistical analysis. P values are shown from Tukey's multiple comparisons for post hoc analysis. Error bars represent standard deviation. Red bars indicate statistical significance due to MTZ treatment. ^*P < 0.05, ^*^*P < 0.01, ^**^*P < 0.001, ^***^*P < 0.0001. For mfrp⁺^/^? untreated, n = 11; for mfrp⁺^/^? MTZ treated, n = 14; for mfrp^?^/^? untreated, n = 15; for mfrp^?^/^? MTZ treated, n = 9.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.