Fig. 4
Laminin receptor beta-dystroglycan is not required for laminin-111 protein re-expression at 3.5 dpf in spns1?/? larvae. (A?F1) Anterior left, dorsal top, side-mounted embryos, and larvae. dag1?/? and spns1?/?; dag1?/? embryos and larvae stained with phalloidin (white) and laminin-111(cyan), (A?F) Merged phalloidin and laminin-111 channels and (A1?F1) single beta-dystroglycan channel over time. (A?F) White arrowheads point to dystrophic lesions and (A1?F1) white arrowheads point to laminin-111 staining. (G) Relative laminin-111 fluorescent intensity over time in spns1?/?; dag1?/? embryos and larvae. Scale bars 50 µm.