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Fig. 4
Laminin receptor beta-dystroglycan is not required for laminin-111 protein re-expression at 3.5 dpf in spns1−/− larvae. (A–F1) Anterior left, dorsal top, side-mounted embryos, and larvae. dag1−/− and spns1−/−; dag1−/− embryos and larvae stained with phalloidin (white) and laminin-111(cyan), (A–F) Merged phalloidin and laminin-111 channels and (A1–F1) single beta-dystroglycan channel over time. (A–F) White arrowheads point to dystrophic lesions and (A1–F1) white arrowheads point to laminin-111 staining. (G) Relative laminin-111 fluorescent intensity over time in spns1−/−; dag1−/− embryos and larvae. Scale bars 50 µm.