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Fig. 6
Degradation of sfGFP-Vangl2 in foxj1a-positive cell lineages causes embryonic axial curvature and postembryonic idiopathic-like scoliosis.
Overview of body axis phenotypes observed in control (a) and vangl2sfGFP/sfGFP;Tg(βactin2::loxP-mCherry-STOP-loxP-zGrad);Tg(foxj1a::iCre) embryos (b–e) at 3 dpf. Lateral and dorsal projections of 3-dimensional micro-CT scans of 2 month old control (f) and vangl2sfGFP/sfGFP;Tg(βactin2::loxP-mCherry-STOP-loxP-zGrad);Tg(foxj1a::iCre) fish (g–i).
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Full text @ Nat. Commun.