ZFIN Image: Kubra et al., 2022, Fig. 3

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Figure Caption

Fig. 3

Schematic representation of human and zebrafish FOS proteins. Depicted are human and zebrafish sequences related to c-FOS (A), FOSB (B), FOSL1 (C), and FOSL2 (D). Functional regions indicated are the basic leucine zipper (bZIP) including the basic region for DNA interaction (orange box) and leucine zipper for dimerization (red box), N-terminal transactivation domain (N-TA), homology box one and two (HOB1, HOB2), proline-rich motif (PRM), C-terminal transactivation motif (C-TM), transactivation domain (TBD), and destabiliser region (C-DEST). Previously characterised phosphorylation (P) sites curated in the Phosphosite database (phosphosite.org (accessed on 24 July 2022)) are indicated. The percentage identity within the bZIP domain and overall protein are indicated by blue dotted or solid lines and text, with the protein length indicated on the left in black text.

Acknowledgments

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