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Fig. 2
Effect of antiseizure medications (ASMs) on ictal-like seizure events in stxbp1b mutant zebrafish. Individual value plots of ictal event frequency at baseline (0–15 min) and 45–60 min after continuous bath application of a test drug. Independent experiment pairs are indicated by the connected line. A, 1 mM phenytoin (PHT, n = 13); not significant (ns) P = .3364. B, 1 mM valproate (VPA, n = 8); not significant (ns) P = .1274. C, 1 mM ethosuximide (ESX, n = 11); not significant (ns) P = .5364. D, 1 mM levetiracetam (LEV, n = 9); not significant (ns) P = .5337. E, 1 mM diazepam (DZP, n = 12); not significant (ns) P = .5330. Student’s unpaired t tests
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