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Fig. 4
Bacterial loads and metabolic profiles of the blood of wild type and ob/ob mice with and without Mtb infection. A Total CFU (1:100 diluted) of the lungs from the WT and ob/ob mice in the absence and presence of infection. CFU colony forming unit, WT wild type. *p < 0.05, **p < 0.01, ****p < 0.0001. B Total CFU (undiluted) of the spleen from the four groups. ***p < 0.001. C PLS-DA analysis of the blood metabolic profiles measured by mass spectrometry from the four mouse groups. PLS-DA partial least square discriminant analysis. D Heatmap analysis of the blood metabolic profiles measured by mass spectrometry from the four mouse groups