The involvement of adenosine receptors in zebrafish pronephros repair. (A) In situ hybridization revealed upregulation of zebrafish adora1a and adora1b after a laser-induced injury. Images were obtained two hours after the injury. (B) Depletion of zebrafish adora1a or adora1b by splice- (SBM) or translation- (TBM) blocking morpholino oligonucleotides (MO) delayed the repair process. (C) In situ hybridization revealed upregulation of zebrafish adora2aa and adora2ab after a laser-induced injury. Images were obtained two hours after the injury. (D) Depletion of zebrafish adora2aa or adora2ab by SBM delayed the repair process (mean ± SEM; 2-way ANOVA).
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Full text @ Int. J. Mol. Sci.
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