ZFIN Image: Lee et al., 2022, Fig. 5

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Fig. 5

Upregulated Fmnl2 and altered gliovascular interactions observed in chronic APP/PS1dE9 AD model in mice. a, h Triple immunohistochemical stainings (tIHC) for Gfap (astroglia), 4G8 (amyloid plaques) and Fmnl2 with DAPI counterstain in control (a, d) and APP/PS1dE9 mice (e–h) at 12 months of age. Panels are from cerebral cortex. Black-white panels are individual fluorescence channels of the composite images in a and e. i–p tIHC for Gfap, Cd31 (blood vessel) and Fmnl2 with DAPI counterstain in control (i–l) and APP/PS1dE9 mice (m–p) at 12 months of age. Panels are from cerebral cortex. Black-white panels are individual fluorescence channels of the composite images in i and m. Scale bars as indicated

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