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Fig. 5
Figure 5. Gprc5b−/− mice die postnatally and exhibit growth restriction. (A,B) Representative images of Gprc5b+/+ (left) and Gprc5b−/− (right) mice at postnatal days 7 (A) and 21 (B), showing marked growth restriction in Gprc5b−/− mice. (C) Survival curve shows ~25% loss of Gprc5b−/− mice prior to weaning. (D) Quantitation of growth restriction and death phenotypes by genotype from heterozygous Gprc5b+/− intercrosses.
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