Fig. 8

Fig. 8

Effects of neuroactive drugs on the behaviour of 6-dpf WT and heterozygous sa17298 larvae in the light-dark test. Larvae were exposed to different neuroactive drugs. Each dot represents individual larval measurement. Data analysed using two-way ANOVA followed by multiple comparison t test. Data represented as mean ± SD. a 2-h RISP, b 24-h RISP, c 2 h HALO and d 2-h VPA. ctl, control; HALO, haloperidol; RISP, risperidone; VPA, valproic acid. *p < 0.05, **p < 0.01, ***p < 0.001 [cacna1da^WT/WT vs cacna1da^sa17298/WT] in respective groups. ^###p < 0.001, ^####p < 0.0001 [cacna1da^WT/WT vs cacna1da^WT/WT] and [cacna1da^sa17298/WT vs cacna1da^sa17298/WT]