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Figure 2.
Hemolytic stress augments the hematopoietic phenotype in Rps14+/− mutants and is rescued by imiquimod. (A) Hemolytic stress experiment. (B-C) Representative views (ventral) of rps14+/+ and rps14+/− siblings treated as in panel A and stained with o-dianisidine at 6 dpf. Rps14+/− mutants demonstrate a clear anemic phenotype, quantified in panel D. (E) Effect of hemolytic stress on HSPCs. Statistical comparisons were performed with Fisher’s exact test (D) or ANOVA (E).
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