ZFIN Image: Banerjee et al., 2022, Figure 1

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Figure Caption

Figure 1

Schematic representation comparing the lengths and interaction domains of human VPS11 and VPS11(C846G) with zebrafish Vps11(plt) and Vps11(−/−). (A) Top: Schematic representation of full-length human VPS11 protein, showing multiple highly-conserved protein domains. Lines above show the putative interactive domains with other Vps effectors based largely on work done in yeast. Below: Schematic representations of human VPS11(C846G), zebrafish Vps11(plt), and zebrafish Vps11(−/−), resulting in presumptively shorter truncated protein products. Note that zebrafish and human sequences do not show 100% nucleic acid identity, but do show conserved protein domains.

Acknowledgments

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