IMAGE

FIGURE 7

ID

ZDB-IMAGE-220205-23

Genes

Antibodies

Ab9-mapk

Source

Figures for Song et al., 2022

Image

Figure Caption

FIGURE 7 Loss of MAPK signaling response to EGF in egfra mutant ovary. (A) EGF treatment of ovarian fragments in vitro induced phosphorylation of MAPK3/1 (Erk1/2) in egfra+/− but not egfra−/− follicles. However, the mutant ovary showed higher basal level of MAPK phosphorylation despite its lack of response to EGF. (B) Immunohistochemical staining for MAPK3/1 phosphorylation in the control and mutant ovaries without EGF treatment. High level of phosphorylated MAPK3/1 was located in the somatic follicle cells of the egfra−/− ovary. (C) Increased expression of chemokine ligands (ccl25b, ccl34b.1, ccl34b.8, and ccl35.2) in egfra−/− follicles.

Figure Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol