ZFIN Image: Chow et al., 2022, Fig 8

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Figure Caption

Fig 8

Delamination defects in gata1 mutants leads to increased cell proliferation.

(A) Number of cells in different valve regions at 98 hpf. p-Values based on unpaired t test. (B) Representative images of 98 hpf gata1 control and mutant valves incubated with EdU from 74 to 98 hpf. Scale bars: 20 μm. (C) Graph showing number of EdU positive cells in 98 hpf gata1 controls and mutant valves. p-Values are based on unpaired t tests. (D) Graph showing fraction valve cells that stained positive for EdU in 98 hpf gata1 controls and mutant valves. p-Values are based on Welch t test. (E) Graph showing fraction of abluminal and luminal cells in 98 hpf gata1 controls and mutant valves that stained positive for EdU. p-Values are based on 2-way ANOVA. AVC, atrioventricular canal; hpf, hours postfertilization; VIC, valve interstitial cell.

Acknowledgments

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