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FIGURE 1
Multiple sequence alignment and phylogenetic analysis of PcActx peptide from P. caribaeorum. (A). Multiple sequence alignment of PcActx peptide and TRPV1 blockers originating from sea anemone, as well as Kv blockers originating from sea anemone and snake. Residues highlighted in blue are the key sites interacting with ion channels. Residues highlighted in red are the interactive sites of PcActx peptides binding to the TRPV1 channel. The arrow symbols represent β-sheet, and the semicircle represents β-turn. (B). Phylogenetic tree of PcActx peptide.
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