Image
|
Figure Caption
Figure 1
Zebrafish hcn2b gene, Human HCN2 and zebrafish Hcn2b protein alignment and the Hcn2b Δ89 allele. (A) Exon-intron organization of the zebrafish hcn2b. The three sgRNA Cas9-targeted are in the first exon. Bold grey letters represent the 89 pb deletion of the hcn2b−/− allele. (B) Alignment of predicted primary sequences of human HCN2 and zebrafish Hcn2b. Similar amino acids are highlighted in blue. (C) Primary sequence of the 18 amino acids predicted in the hcn2b−/− allele.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Int. J. Mol. Sci.