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Figure 5
Seizures induced by flashlights in the hcn2b−/− mutant. During dark-light transitions, about 7% of adult hcn2b−/− mutants exhibited behavioral seizure activity. (A) First, fish increased their swimming activity (Stage I); then, they showed a rapid “whirlpool-like” circling swimming behavior (Stage II); finally, they exhibited a series of brief clonus-like convulsions that led to a loss of posture and immobility (Stage III). (B) Snap shot sequences of each stage of the seizures caused by flashlight in the hcn2b−/− mutant zebrafish. Images taken from Video S2.
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Full text @ Int. J. Mol. Sci.