FIGURE 5
Figure 5. Magnetic resonance imaging of wild-type and U-box− /− zebrafish brains demonstrate similar intact structures. MRI of the adult zebrafish brain at 24 months revealed no significant alterations in the overall brain structures between wild-type (A) and mutant (B) zebrafish. (C) Different regions of a wild-type zebrafish brain are indicated on a representative MRI image. Section area of the whole brain (D,E) the relative area of different regions (D) were calculated by using Fiji (ImageJ) software (31). Data shown are means and error bars indicate standard deviations (∗p < 0.05, Student’s t-test). Scale bars in (A–C): 1 mm. Te, telencephalon; TeO, tectum opticum; Cce, corpus cerebelli; Mo, medulla oblongata.