Figure 6
Histological examination of wild-type, eysKO and eysΔexon40-44 zebrafish retinas. Light microscopy of retinal sections from adult zebrafish (15 months post fertilization (mpf)) stained with hematoxylin (purple) and eosin (red). Retinas of the eysΔexon40-44 and eysKO lines are morphologically indistinguishable. In both the eysΔexon40-44 and eysKO retinas, a reduction of the thickness of all retinal layers was observed as compared to wild-type controls. In addition, photoreceptor outer segments seem to be shortened and disorganized in both eysΔexon40-44 and eysKO as compared to wild-type retinas. Scale bar: 20 μm. RPE: retinal pigment epithelium, ONL: outer nuclear layer, OPL: outer plexiform layer, INL: inner nuclear layer, GCL: ganglion cell layer.