ZFIN Image: Lima Cunha et al., 2021, Figure 2

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Figure Caption

Figure 2 CHM patients exhibit evidence of increased oxidative stress. (A) Schematic of the glutathione metabolism pathway, where several compounds were found to be increased (red) or decreased (green) in CHM patients compared with controls. Metabolites trending to significance (0.05 < P ≤ 0.1) are represented in a lighter shade to distinguish from those significantly altered (P ≤ 0.05). (B–I) Scatter dot plots of specific metabolites indicating the mean ± SD levels in CHM patient samples (red) and control samples (blue) (n = 25). P value was determined using matched pair t tests. #0.05 < P ≤ 0.1, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001.

Acknowledgments

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