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Fig 9 (A-D) Flat mounts of 5dpf gata3 b1075/b1075 neurocrania anterior to the left. (A-B) control untreated-embryos from the gata3 “severe” background showing normal stacking and fusion of trabeculae. Both of (A) wild type and (B) heterozygotes develop normally. (C-D) Cyclopamine-treated embryos. (C) Wild type embryo showing normal stacking and fusion of trabeculae (n = 22/22). (D) Heterozygote embryo displaying complete loss of trabeculae with severe clefts (n = 6/61).
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