ZFIN Image: Wong et al., 2021, Fig. 3

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Figure Caption

Fig. 3

TEM of 4-dpf larvae injected with control or mvda morpholinos. A, B Keratinocytes of the control group revealed regular arranged spicules (black arrows) and cytoplasmic keratin filaments. C, D Keratinocytes of the mvda-e3i3-MO-injected zebrafish revealed disorganized spicules (black arrows), disordered cytoplasmic keratin filaments, distended rough endoplasmic reticulum (yellow asterisks), swollen mitochondria (red circle), autophagosomes and mitophagy (red arrowheads), vesicles (red asterisks), and rupture of cell–cell contacts (blue asterisk). Open arrowheads point to the basement membrane; e, epidermis; d, dermis; cs, collagenous stroma; dpf, days post fertilization. Scale bars = 1 µm (A, C) and 0.5 µm (B, D)

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Phenotype details

Acknowledgments

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