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Fig. 3 3,4-Diaminopyridine phosphate improved NMJs in zebrafish embryos. (A) Electron micrographs showing a swollen and convoluted end-plate in a morphant, a normal appearing end-plate in a 3,4-DAPP treated morphant and a normal endplate in a control embryo. Note the synaptic cleft (white arrows) and active zones (black arrows). Scale bar = 2 µm. (B,C) Quantification of the percentage of NMJs presenting normal structure (B), and of acetylcholine vesicles (C), in the three experimental groups. Error bars are SEMs.
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