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Fig. 5 Loss of Aqp0a and Aqp0b alters lens maximum refractive index growth. Lens refractive index as a function of lens diameter (A) and age (dpf) (B) for WT, aqp0a−/−, aqp0b−/−, and double aqp0a−/−/aqp0b−/− mutants. Lens maximum refractive index growth followed a similar trend and plateaued close to 1.58 at lens diameters over ∼650 µm (A) and in fish over ∼40 dpf (B). Double aqp0a−/−/aqp0b−/− mutant lens maximum refractive index growth did not plateau and reached a maximum attained value of ∼1.57 at lens diameters of ∼900 µm (A) and fish over ∼150 dpf (B).
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Full text @ Invest. Ophthalmol. Vis. Sci.