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Fig. 5 ER stress is prevalent in tissues outside of the nervous system. Representative images and quantification of 5XATF6RE:d2GFP ER stress in the jaw at 4dpf (A, A’; one-way ANOVA, F = 34.44, p < 0.0001) and 7dpf (B, B’; one-way ANOVA, F = 13.86, p < 0.0008), intestine at 7dpf (C, C’; one-way ANOVA, F = 8.358, p = 0.0053), and muscle at 4dpf (D, D’; one-way ANOVA, F = 8.205, p = 0.0031) and 7dpf (E, E’: F = 5.624, p = 0.0189). * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001. Fish = indicates ctage5-/- tango1-/- mutants do not survive to 7dpf.
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