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Figure 8 Absence of females among myoc KO zebrafish. Eight +/− myoc siblings were mated, and 30–35 embryos per cross were randomly selected (n = 256), raised to adulthood and genotyped by PAGE. The sex ratio as a function of the myoc genotype was calculated (A). Observed genotype proportions (B) and embryo survival (C). Values are expressed as the mean ± standard error of the mean (SEM). Asterisks indicate statistical significance compared to +/+. * p = 0.00038. ** p = 0.00001. +/+: wild-type; −/−: myoc KO.
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