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Figure 6—figure supplement 1.

ID: ZDB-IMAGE-201223-35
Source: Figures for Chin et al., 2020

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Figure Caption

Figure 6—figure supplement 1. RNA-sequencing profiling of cohesin-deficient MCF10A cells. RNA-sequencing profiling of cohesin-deficient MCF10A cells.

(A) Whole genome correlation matrix of MCF10A cells. The dendrogram shows a common clustering of the biological replicates. There are two main clusters. The STAG2-/- (MT10_1–3) transcriptomes are more similar to the WT (MWT_1–3). SMC3+/- (MS_1–3) and RAD21+/- (MR50_1–3) populate the second cluster. (B) MCF10A gene expression profile of genes involved in WNT signaling pathways according to Gene Ontology annotation (GO:0016055). The heatmap shows the clustering of the scaled (z-score) normalized count (log2RPKM) for each replicate. RNA-sequencing data is available in the GEO database under GSE154086.

Acknowledgments

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