(A) Fear acquisition was observed in conditioned mice (C+), while unconditioned controls (C-) did not show freezing behavior during initial context exposure (TR). In the memory retrieval session (RET), conditioned mice showed strong freezing behavior, while unconditioned mice did not freeze in response to the training context (X2(3) = 20.894, p<0.001, NTR C- = 7, NTR C+ = 6, NRET C- = 7, NRET C+ = 6, Kruskal-Wallis ANOVA followed by pairwise Mann-Whitney tests with Bonferroni correction, *p<0.05). (B) Distance traveled in the training context is reduced in fear conditioned mice (F(3, 22) = 19.484, p<0.001, NTR C- = 7, NTR C+ = 6, NRET C- = 7, NRET C+ = 6, one-way ANOVA followed by pairwise t-tests with Bonferroni correction, **p<0.01, ***p<0.001). Source data is available as Figure 3-figure supplement 1 source data 1.
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