ZFIN Image: Wang et al., 2020, FIGURE 5

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Figure Caption

FIGURE 5

Correlation between clinical features and Gene Ontology (GO) enrichment analysis of clinical feature-related variants. (A) The association between each clinical feature is depicted. The strength of the association is represented by the intensity of the red color. (B) Venn diagram of the distribution of each clinical feature-related variant as identified in our study (blue circle = location of apical vertebrae, yellow circle = Cobb angle, green circle = main curve direction, and pink circle = number of tilted vertebrae). (C) GO enrichment analysis of the filtered variants was performed. GO biological process (BP) annotation is indicated on the left. Each individual box represents a clinical characteristic. The –Log10 (P-value) value is represented by color intensity, and the gene ratio is indicated by the size of the circle.

Acknowledgments

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