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Fig. 2 Histological analysis of early gonadal development in the amh mutant. The gonads at 25 dpf were mostly undifferentiated in both amh control (amh+/−) and mutant (amh−/−), whereas well-developed perinucleolar PG follicles and clustered pre-meiotic spermatogonia were found at 30 dpf in the ovary and testis respectively. At 45 dpf, puberty onset had started in females as evidenced by the PV follicles containing cortical alveoli, and spermatogenesis in the testes had entered meiotic phase with large number of spermatocytes and even mature spermatozoa. The arrows indicate the oocyte-like germ cells. PG, primary growth follicles; PV, pre-vitellogenetic follicles; SG, spermatogonia in cysts; SC, spermatocytes; SZ, spermatozoa.
Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.