Figure 2—figure supplement 2.

Figure 2—figure supplement 2.

(A) Scatter plot displaying the log2-fold change of genes differentially expressed between Cherry⁺ and Cherry^- samples in the adult zebrafish bulk transcriptomic study presented in this article (X axis) and the log2-fold change of genes differentially expressed between mouse ENS neuron and ENS glia in a published single cell dataset published by Zeisel and colleagues (Zeisel et al., 2018) (Y axis). Full data in Supplementary file 3 (see also Methods and Figure 2—figure supplement 3). Genes up in Cherry+ and up in mouse neurons are found in the lower right quadrant, with example genes highlighted in red. Genes up in Cherry+ and up in mouse glia are found in the upper right quadrant, with example genes highlighted in green. (B) Clustered heat map showing the list of 366 genes enriched in mouse ENS neurons (logFC >0.2 mouse neurons vs. glia) whose zebrafish orthologues are enriched in the Cherry+ population (logFC >0, p-value≤0.05) analysed in the adult zebrafish gut transcriptomic data of this study. Select genes shown (full gene list and corresponding data shown in Supplementary file 4). (C) Clustered heat map showing the list of 63 genes enriched in mouse ENS glia (logFC >0.2 mouse glia vs. neurons) whose zebrafish orthologues are enriched in the Cherry+ population (logFC >0, p-value≤0.05) analysed in the adult zebrafish gut transcriptomic data of this study (full gene list and corresponding data shown in Supplementary file 5).