IMAGE

Figure 1

ID
ZDB-IMAGE-200807-15
Source
Figures for Meshalkina et al., 2020
Image
Figure Caption

Figure 1

The mechanisms of action of LbCas12a (a) and SpCas9 (b) nucleases. LbCas12a cleaves far from PAM and SpCas9 cleaves near PAM, in the seed region. TTTN -represents the PAM sequence for LbCas12a, NGG is the PAM sequence for SpCas9, cleavage sites by nuclease domains (RuvC and HNH) are labeled with red triangles (pink triangle labels an alternative cut site, producing staggered ends).

Acknowledgments
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