ZFIN Image: Song et al., 2020, Fig. 2

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Figure Caption

Fig. 2

Kiss2 neurons (red) and Gnrh3 fibers (green) in the zebrafish pituitary. (A) The distribution of Gnrh3 nerve fibers in the female pituitary. A very large number of Gnrh3 axonal projections penetrate the proximal pars distalis (PPD). (B) Kiss2 nerve structures distribute though the female pituitary. (C) Kiss2 fibers show a similar distribution pattern to that of Gnrh3 fibers in the PPD regions. (D) Gnrh3 fiber bundles invade through the pituitary stalk (rectangular frame), but no Kiss2 fibers are detected in the pituitary stalk. The Kiss2 cells (arrow, high-resolution image) and fibers arise near the pituitary stalk. (E) Kiss2 neurons (arrow, high-resolution image) and fibers (asterisk) reside side by side with Gnrh3 nerve bundles penetrating the neurohypophysis (NH). (F) Gnrh3 fibers are contacted by Kiss2 fibers in the PPD. Kiss2 cells (arrow, high-resolution image) are detected in this area. (G) Gnrh3 fibers are detected in the male pituitary. (H) Kiss2 fibers are rarely found in the male pituitary. (I) Gnrh3 fibers are not in contact with Kiss2 fibers in the male pituitary.

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 513, Song, Y., Chen, J., Tao, B., Luo, D., Zhu, Z., Hu, W., Kisspeptin2 regulates hormone expression in female zebrafish (Danio rerio) pituitary, 110858, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.