Image
|
Figure Caption
Fig. s3 FGF signaling is required for aggregation of cells into nephrogenic condensates. (A) Nephrogenic aggregates are apparent in histological sections as compact basophilic structures adjacent to distal tubules at 7 dpi. Arrows indicate nascent nephrons. (B) FGF inhibition with PD166866 post-injury prevents the formation of nephrogenic aggregates, and no peri-tubular basophilic cellular aggregates can be found in histological sections. Scale bars are 50 μm.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 454(1), Gallegos, T.F., Kamei, C.N., Rohly, M., Drummond, I.A., Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney, 44-51, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.