Fig. 11
Effect of UBE3D on the Migration of hRPE Cells
(A) shows RPE through Boyden upper compartment (DAPI staining, RPE-colored nuclei through the compartment as seen under fluorescence microscopy). (B) Statistical results. The migratory activities of cell lines were estimated based on the numbers of cells that had migrated through the filter of the chamber. The numbers of migrating cells in the UBE3D-overexpressing group were greater than those observed in the lentiviral vector control group. The numbers of migrating cells in the low-UBE3D-expressing group were lower than those observed in the lentiviral nonspecific control group (∗p < 0.05).