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Fig. 6
Knockdown of ube3d Results in Delayed Epinephrine-Induced Melanosome Retraction
(A and B) WT 120-hpf larvae prior to treatment (A) and at 4 min after exposure to epinephrine (B). (C and D) e2-MO 120-hpf larvae prior to treatment (C) and at 4 min after exposure to epinephrine (D). (E) A graphical representation demonstrating that epinephrine-induced melanosome retrograde trafficking was significantly slower in e2-MO 120-hpf larvae (11.0 ± 0.5 min) than trafficking in WT larvae (2.32 ± 0.64 min). The data are presented as the mean ± SD. ∗∗p < 0.01.
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