ZFIN Image: Volpatti et al., 2020, Figure 2-figure supplement 2

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Figure Caption

Figure 2-figure supplement 2 Post-hoc statistical analysis showing that 142 chemicals out of the 278 chemicals identified from the primary screen produced developmental stage distributions that were significantly different from random escapee wells (red arrows).

It is important to note that this was performed with the assumption that 20 worms were in each well as a means of estimating the proportion of actual L4 and adult counts in each well. In other words, we assumed #L1-L3 larvae = 20 – (#L4 + #adult). Plots shown are from independent screens of (A) 7.5 μM wactives, (B) 60 μM wactives, (C) 60 μM ‘random’ non-wactives, and (D) 60 μM US Drug Collection. Statistical analysis by Kruskal-Wallis test with Dunn’s multiple comparisons post-test where *p<0.05, **p<0.01, ***p<0.001.

Acknowledgments

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