ZFIN Image: de Oliveira et al., 2020, Fig. 2.

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Figure Caption

Fig. 2.

Overexpression of Dnajb1a-Prkacaa(zfDnaJa-Pkaca)can induce liver masses at adult stages. (A) Representative maximum-intensity projections (MIPs) of 7 day post-fertilization (dpf) FLC larvae [Tg(fabp10a:dnajb1a-prkacaa)/Tg(fabp10a:egfp-l10a)] and control siblings [Tg(fabp10a:egfp-l10a)]. (B) Chi-square graphs showing percentages of fish with masses (8 months, control N=5, FLC N=8; 12 months, control N=5, FLC N=7). (C) Representative images of H&E staining of the livers of 12-month-old fish at 10× and 40× magnification. Yellow outlines delineate masses, white arrowheads indicate prominent nucleoli and black arrowheads indicate lipid vacuoles. Scale bars: 60 μm (10× magnification) and 10 μm (40× magnification). M, mass; N, normal tissue.

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Acknowledgments

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