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Fig. 1 Maternal-effect cleavage-stage mutants. A. Developmental arrest mutants and wild-type at 2.25 hpf (top row) and at 5.0 hpf (bottom row). For each mutant the phenotype is 100% penetrant within a clutch and across mutant females. At least 50 embryos per mutant female were examined (n = 233 from four srh females, n = 854 from six bmb females, n = 335 from four p10umal females). B. Irregular cleavage mutants and wild type at 0.75 hpf (top row), 1.0 hpf (middle row) and 1.25 hpf (bottom row). Five of 6 mxp females produced embryos shown (n = 459), while one produced embryos with a more mild phenotype (n = 91). C. Wild-type (top row) and cld mutants (bottom row) at 1.0, 1.5, and 4.0 hpf. Penetrance of the cell sloughing phenotype (black arrow) at 4.0 hpf is indicated in lower left corner. Remaining embryos retain relatively normal, but dark, blastoderms and do not survive to 24 hpf.