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Figure 4
Light induced aggregation causes physical disruption of embryonic neural tissues.
(a–a’’) Elav-Gal4/UAS-Aβ-CRY2-mCh embryos kept in the dark and imaged for neurons (Elav) and glial cells (Repo). (b–b’’) Elav-Gal4/UAS-Aβ-CRY2-mCh embryos exposed to light and imaged for neurons (Elav) and glial cells (Repo). (c–d’’) Close ups. (E) Aggregation induced inflammatory response as measured by qPCR for inflammatory response genes. (f) The number of mitochondria in transgenic Aβ Drosophila embryo was reduced by 40% in light.
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