ZFIN Image: Villasenor et al., 2019, Fig. 1

Image

Figure Caption

Fig. 1 hhex−/− display impaired liver and pancreas development. (A–C) Analysis of the endodermal phenotypes in hhex−/−. (A) Lateral views of 96 hpf Tg(fabp:GFP) hhex+/+ sibling and hhex−/− larvae. (B) Maximum intensity projections of 96 hpf hhex+/+ sibling and hhex−/− larvae. Ventral views, anterior to the top. hhex−/− display impaired liver development. (C) Dorsal views of whole-mount in situ hybridization for ptf1a expression at 32 and 72 hpf. Compared to stage-matched hhex+/+ siblings, hhex−/− lack exocrine tissue specification, but they display ptf1a neural expression. Black arrows point to pancreatic exocrine tissue. H, heart; L, liver; P, pancreas. Scale bars: 50 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 458(2), Villasenor, A., Gauvrit, S., Collins, M.M., Maischein, H.M., Stainier, D.Y.R., Hhex regulates the specification and growth of the hepatopancreatic ductal system, 228-236, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.