ZFIN Image: Bryan et al., 2020, Fig. 6.

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Figure Caption

Fig. 6.

Nid1a overexpression partially rescues optic cup morphogenesis in tfap2a;foxd3 mutants. (A-D′) Double-transgenic embryos [Tg(bactin2:EGFP-CAAX);Tg(hs:WT-Nid1a)]: sibling control and tfap2a;foxd3 mutant embryos not heat shocked (A-B′), or heat shocked at 12-13 hpf (C-D′). Dorsal view, single confocal sections, 24 hpf. (E-G) Quantification of invagination angle (E), optic fissure angle (F) and lens roundness (G). n (embryos) shown in the base of the graph, from two or three experiments. P-values were calculated using one-way ANOVA with Tukey HSD post-hoc test. Scale bar: 50 μm. L, lateral; M, medial; N, nasal; T, temporal.

Figure Data

Phenotype details

Acknowledgments

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