ZFIN Image: Li et al., 2020, Figure 6

Image

Figure Caption

Figure 6 Loss of <italic>celsr1a</italic> leads to altered polarity phenotypes in the zebrafish integument.

(A–B) Alizarin red stained adult wild-type zebrafish showing pattern of scales on the flank. (A). Wild-type fish showing normal, regularly spaced pattern of scales whereas, in (B) frnt mutants show altered patterning of scales across the flank, creating swirls. (C) Wild-type scale showing internal polarity of growth along the rostrocaudal axis (bottom to top). (D) frnt scale showing radial pattern of growth rings (annuli), without the internal polarity normally observed in wild-type. (E) Quantification of polarity in wild-type sibling and frnt scales (n = 6 fish,>25 scales each side) as indicated by the ratio of the center-to-base normalized by the diameter for each scale (C, D). Data presented as mean ± standard deviation; ****p<0.001.

Figure Data

Phenotype details

Acknowledgments

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