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Figure 1
Schematic diagram of vitamin B6 metabolism. B6 vitamers, including pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), can be phosphorylated to pyridoxine 5′-phosphate (PNP), pyridoxal 5′-phosphate (PLP), and pyridoxamine 5′-phosphate (PMP) by pyridoxal kinase. The phosphorylated form of B6 vitamers can also be hydrolyzed by pyridoxal phosphatase. The conversion of PNP/PMP to PLP requires an active pyridoxine 5′-phosphate oxidase (PNPO).
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