ZFIN Image: Gudmundsson et al., 2019, Fig. S2

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Figure Caption

Fig. S2

Comparison of two different taf1 knockout strains. (A) Schematic overview of deletions in two different strains, taf1^{uu1931/ uu1931} p.(Gly296Leufs*2) and taf1^{uu1941/ uu1941} p.Glu362Alafs*9. (B) Four zebrafish embryos of both taf1^{uu1931/ uu1931} and taf1^{uu1941/ uu1941}at 4 days post-fertilization show a similar abnormal phenotype compared to wild-type taf1 zebrafish (left). The malformations were lethal and included general developmental delay, reduced pigmentation, underdeveloped craniofacial cartilage, cerebral edema, underdeveloped and malformed ears, dorsally bent body axis, heart edema, blood-filled cavities, short pectoral fin, and underdeveloped eyes with coloboma.

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Acknowledgments

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