ZFIN Image: Fontenas et al., 2019, Fig. S1

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Figure Caption

Fig. S1

Blocking of vesicular release results in larval paralysis. (A) Percentage of embryos that were mobile or paralyzed during dechorionation with forceps at 2 dpf. Analyzed by Chi-squared test; ***p<0.0001, n = 54 (WT), n = 57 (TeNT). (B) Percentage of fish with positive and negative startle responses at 3 dpf. Analyzed by Fisher’s exact test; ***p<0.0001, n = 52 (WT), n = 53 (TeNT). (C) Brightfield images of 3 and 5 dpf WT and adora2ab-/- siblings injected with TeNT mRNA at the one-cell stage. Note that in the 5 dpf larvae, neither WT nor adora2ab mutants have inflated swim bladders because of their inability to swim and get to the surface of the petri dish to gulp air in order to inflate their swim bladder. (D) Brightfield images of 3 dpf WT and gpr126-/- siblings injected with TeNT mRNA at the one-cell stage. Scale bars (C&D), 0.5 mm.

Acknowledgments

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