ZFIN Image: Cheng et al., 2019, Fig. 7

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Figure Caption

Fig. 7

Functional interaction between Cthrc1a and integrin β1 in axis extension. (A) Embryos were injected with CoMO, low dose of dnß1 mRNA, low dose of cthrc1MO, or a mixture of cthrc1MO and dnß1 mRNA at 1-cell stage, statistical analysis of the extent of hypoblast migration in different injected embryos was performed at bud stage, as shown in the inset image. A total of 12 embryos randomly selected from 3 independent experiments were analysed for each condition. Numbers in each column represent total embryos injected. The results are expressed as mean ± s.d. from three independent experiments (*, P < 0.05; **, P?<?0.01; Student's t-test). (B–E) Representative phenotypes for each condition at 27 hpf, as indicated. Scale bar: (B–E) 500?μm.

Acknowledgments

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